Polycystic Ovary Syndrome
September 2018 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Polycystic Ovary Syndrome abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Polycystic Ovary Syndrome. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Polycystic Ovary Syndrome. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Polycystic Ovary Syndrome every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Aromatase inhibitors (letrozole) for subfertile women with polycystic ovary syndrome.
Authors:Franik S, Eltrop SM, Kremer JA, Kiesel L, Farquhar C
Institution:Department of Obstetrics and Gynaecology, University Hospital Munster, Albert-Schweitzer-Campus 1, Munster, Germany, 48149.
Journal:Cochrane Database Syst Rev. 2018 May 24;5:CD010287. doi: 10.1002/14651858.CD010287.pub3.

2:Liraglutide increases IVF pregnancy rates in obese PCOS women with poor response to first-line reproductive treatments: a pilot randomized study.
Authors:Salamun V, Jensterle M, Janez A, Vrtacnik Bokal E
Institution:Division of Obstetrics and GynecologyDepartment of Human Reproduction vesna.j.salamun@gmail.com. Centre Ljubljana, Ljubljana, Slovenia. Centre Ljubljana, Ljubljana, Slovenia.
Journal:Eur J Endocrinol. 2018 Jul;179(1):1-11. doi: 10.1530/EJE-18-0175. Epub 2018 Apr 27.

3:The role of lifestyle changes in the treatment of polycystic ovary syndrome.
Authors:Smyka M, Grzechocinska B, Wielgos M
Institution:1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Poland. Poland. Poland.
Journal:Neuro Endocrinol Lett. 2018 Feb;38(8):521-527.

4:The Efficacy of 24-Month Metformin for Improving Menses, Hormones, and Metabolic Profiles in Polycystic Ovary Syndrome.
Authors:Yang PK, Hsu CY, Chen MJ, Lai MY, Li ZR, Chen CH, Chen SU, Ho HN
Institution:Department of Obstetrics and Gynecology, National Taiwan University Hospital Yunlin Branch, Douliu, Taiwan. Taipei, Taiwan. Taipei, Taiwan. University, Taipei, Taiwan. Taipei, Taiwan. Taipei, Taiwan.
Journal:J Clin Endocrinol Metab. 2018 Mar 1;103(3):890-899. doi: 10.1210/jc.2017-01739.

5:Laparoscopic ovarian drilling reduces serum homocysteine levels in women with Polycystic Ovary Syndrome.
Authors:Chitra T, Papa D, Sinha P, Nandeesha H
Institution:Department of Obstetrics and Gynecology and Biochemistry, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, 605006, India. Electronic address: drchitra@yahoo.com.
Journal:Eur J Obstet Gynecol Reprod Biol. 2018 Feb;221:135-138. doi: 10.1016/j.ejogrb.2017.12.048. Epub 2017 Dec 27.

6:Insulin resistance improvement by cinnamon powder in polycystic ovary syndrome: A randomized double-blind placebo controlled clinical trial.
Authors:Hajimonfarednejad M, Nimrouzi M, Heydari M, Zarshenas MM, Raee MJ, Jahromi BN
Institution:Research Center for Traditional Medicine and History of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Incubator, Shiraz University of Medical Sciences, Shiraz, Iran. University of Medical Sciences, Shiraz, Iran. Incubator, Shiraz University of Medical Sciences, Shiraz, Iran. University of Medical Sciences, Shiraz, Iran. Incubator, Shiraz University of Medical Sciences, Shiraz, Iran. Sciences, Shiraz, Iran. Shiraz University of Medical Sciences, Shiraz, Iran. Pharmaceutical Sciences Research Centre, Shiraz University of Medical Sciences, Shiraz, Iran. Medical Sciences, Shiraz, Iran. Shiraz, Iran.
Journal:Phytother Res. 2018 Feb;32(2):276-283. doi: 10.1002/ptr.5970. Epub 2017 Dec 18.

7:Combined Oral Contraception and Bicalutamide in Polycystic Ovary Syndrome and Severe Hirsutism: A Double-Blind Randomized Controlled Trial.
Authors:Moretti C, Guccione L, Di Giacinto P, Simonelli I, Exacoustos C, Toscano V, Motta C, De Leo V, Petraglia F, Lenzi A
Institution:Department of Systems' Medicine, Unit of Endocrinology, Section of Reproductive Endocrinology, "San Giovanni Calibita" Hospital, University of Rome Tor Vergata, Rome, Italy. Endocrinology, "San Giovanni Calibita" Hospital, University of Rome Tor Vergata, Rome, Italy. Endocrinology, "San Giovanni Calibita" Hospital, University of Rome Tor Vergata, Rome, Italy. Foundation for Health Research and Education, Rome, Italy. Vergata, Rome, Italy. of Rome "Sapienza," Rome, Italy. of Rome "Sapienza," Rome, Italy. of Siena, Siena, Italy. of Siena, Siena, Italy. I" Hospital, University of Rome "Sapienza," Rome, Italy.
Journal:J Clin Endocrinol Metab. 2018 Mar 1;103(3):824-838. doi: 10.1210/jc.2017-01186.

8:Ovarian volume and PCOS: a controversial issue.
Authors:Giampaolino P, Della Corte L, De Rosa N, Mercorio A, Bruzzese D, Bifulco G
Institution:a Department of Public Health , University of Naples Federico II , Naples , Italy.
Journal:Gynecol Endocrinol. 2018 Mar;34(3):229-232. doi: 10.1080/09513590.2017.1391205. Epub 2017 Oct 18.

9:Polycystic ovary syndrome throughout a woman's life.
Authors:Bellver J, Rodriguez-Tabernero L, Robles A, Munoz E, Martinez F, Landeras J, Garcia-Velasco J, Fontes J, Alvarez M, Alvarez C, Acevedo B
Institution:IVI-Valencia, University of Valencia, Valencia, Spain. jose.bellver@ivi.es.
Journal:J Assist Reprod Genet. 2018 Jan;35(1):25-39. doi: 10.1007/s10815-017-1047-7. Epub 2017 Sep 27.

10:The cardiometabolic effect of current management of polycystic ovary syndrome: strategies of prevention and treatment.
Authors:Baldani DP, Skrgatic L, Ougouag R, Kasum M
Institution:a Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility , University of Zagreb, School of Medicine, Clinical Hospital Centre Zagreb , Zagreb , Croatia.; b Medical Student , School of Medicine, University of Zagreb , Zagreb , Croatia.
Journal:Gynecol Endocrinol. 2018 Feb;34(2):87-91. doi: 10.1080/09513590.2017.1381681. Epub 2017 Sep 23.

11:Methylprednisolone for prevention of ovarian hyperstimulation syndrome in patients with polycystic ovarian syndrome undergoing in-vitro fertilisation: a randomised controlled trial.
Authors:Mohammadi Yeganeh L, Moini A, Shiva M, Mirghavam N, Bagheri Lankarani N
Institution:a Department of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center , Royan Institute for Reproductive Biomedicine, ACECR , Tehran , Iran.; b Department of Gynecology and Obstetrics, Roointan Arash women's Health Research and Educational Hospital , Tehran University of Medical Sciences , Tehran , Iran.; c Vali-e-Asr Reproductive Health Research Center , Tehran University of Medical Sciences , Tehran , Iran.; d Department of Epidemiology and Reproductive Health, Reproductive Epidemiology Research Center , Royan Institute for Reproductive Biomedicine, ACECR , Tehran , Iran.
Journal:J Obstet Gynaecol. 2018 Feb;38(2):241-246. doi: 10.1080/01443615.2017.1346593. Epub 2017 Sep 14.

12:Therapeutic approach for metabolic disorders and infertility in women with PCOS.
Authors:Morgante G, Massaro MG, Di Sabatino A, Cappelli V, De Leo V
Institution:a Obstetrics and Gynecology, Department of Molecular and Developmental Medicine , University of Siena , Siena , Italy.
Journal:Gynecol Endocrinol. 2018 Jan;34(1):4-9. doi: 10.1080/09513590.2017.1370644. Epub 2017 Aug 29.

13:Polycystic Ovary Syndrome among Obese Adolescents.
Authors:Ybarra M, Franco RR, Cominato L, Sampaio RB, Sucena da Rocha SM, Damiani D
Institution:a Pediatric Endocrinology Unit , Instituto da Crianca do Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo , Sao Paulo , Brazil.; b Pediatric Radiology Unit , Instituto da Crianca do Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo , Sao Paulo , Brazil.
Journal:Gynecol Endocrinol. 2018 Jan;34(1):45-48. doi: 10.1080/09513590.2017.1359250. Epub 2017 Jul 29.

14:The effects of vitamin D and evening primrose oil co-supplementation on lipid profiles and biomarkers of oxidative stress in vitamin D-deficient women with polycystic ovary syndrome: A randomized, double-blind, placebo-controlled trial.
Authors:Nasri K, Akrami S, Rahimi M, Taghizadeh M, Behfar M, Mazandaranian MR, Kheiry A, Memarzadeh MR, Asemi Z
Institution:a Endocrinology and Metabolism Research Center, Department of Gynecology and Obstetrics , School of Medicine, Arak University of Medical Sciences , Arak , Iran.; b Department of Gynecology and Obstetrics, School of Medicine , Iran University of Medical Sciences , Tehran , Iran.; c Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences , Kashan , I.R . Iran.; d Barij Medicinal Plants Research Center , Kashan , I.R . Iran.
Journal:Endocr Res. 2018 Feb;43(1):1-10. doi: 10.1080/07435800.2017.1346661. Epub 2017 Jul 25.

15:Operative transvaginal hydrolaparoscopy improve ovulation rate after clomiphene failure in polycystic ovary syndrome.
Authors:Giampaolino P, De Rosa N, Della Corte L, Morra I, Mercorio A, Nappi C, Bifulco G
Institution:a Department of Public Health , University of Naples Federico II , Naples , Italy and.; b Department of Neuroscience , Reproductive Sciences and Dentistry, University of Naples Federico II , Naples , Italy.
Journal:Gynecol Endocrinol. 2018 Jan;34(1):32-35. doi: 10.1080/09513590.2017.1323204. Epub 2017 May 11.

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